An approach to gastroprotective analgesia
Keywords:
gastroprotective analgesia, Non-steroidal anti-inflammatory drugs, (NSAIDs)
Abstract
As a class, nonsteroidal anti-inflammatory drugs (NSAIDs) comprise traditional nonselective NSAIDs and selective cyclo-oxygenase-2 inhibitors. NSAIDs are among the most widely used medications in the world because of their demonstrated efficacy in reducing pain, fever and inflammation. NSAIDs have been used for the management of a variety of clinical disorders, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, musculoskeletal injuries, dysmenorrhoea, headaches and dental pain. However, the gastrointestinal toxicity associated with nonselective NSAIDs may cause side-effects that range from mild dyspepsia to gastrointestinal ulceration.
Issue
Section
Reviews
By submitting manuscripts to SAPJ, authors of original articles are assigning copyright to Medpharm Publications (Pty) Ltd. Authors may use their own work after publication without written permission, provided they acknowledge the original source. Individuals and academic institutions may freely copy and distribute articles published in SAPJ for educational and research purposes without obtaining permission.
