Hypertension: a review of antihypertensive medication, past and present
Keywords: hypertension, antihypertensive agents, fixed-dose combination therapy, angiotensin II-receptor blockers, angiotensin-converting enzyme inhibitors, calcium-channel blockers
AbstractThis article provides an overview of the changes that have taken place in the diagnosis and management of hypertension over the past decade. Hypertension remains a very common condition seen in South Africa. The approach to the management of hypertension includes necessary lifestyle modifications and a decisive, stepwise escalation process in the pharmacotherapeutic management thereof. Thiazide diuretics are still being promoted by most guidelines to be the initial (first-line) drug of choice, with the addition of other suitable antihypertensive agents, if necessary, and according to any relevant co-morbid conditions.
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