Hypertension: a review of antihypertensive medication, past and present

  • Natalie Schellack Sefako Makgatho Health Sciences University
  • Pranusha Naicker Sefako Makgatho Health Sciences University
Keywords: hypertension, antihypertensive agents, fixed-dose combination therapy, angiotensin II-receptor blockers, angiotensin-converting enzyme inhibitors, calcium-channel blockers

Abstract

This article provides an overview of the changes that have taken place in the diagnosis and management of hypertension over the past decade. Hypertension remains a very common condition seen in South Africa. The approach to the management of hypertension includes necessary lifestyle modifications and a decisive, stepwise escalation process in the pharmacotherapeutic management thereof. Thiazide diuretics are still being promoted by most guidelines to be the initial (first-line) drug of choice, with the addition of other suitable antihypertensive agents, if necessary, and according to any relevant co-morbid conditions.

Author Biographies

Natalie Schellack, Sefako Makgatho Health Sciences University
PhD (Pharmacy) Associate Professor Department of Pharmacy Faculty of Health Sciences Sefako Makgatho Health Sciences University
Pranusha Naicker, Sefako Makgatho Health Sciences University
BPharm Academic Intern Department of Pharmacy Faculty of Health Sciences Sefako Makgatho Health Sciences University
Published
2015-03-02
Section
Reviews