Gastro-oesophageal reflux disease: a pharmacist’s perspective for 2020
Gastro-oesophageal reflux disease (GORD) produces symptoms that cause great irritation and discomfort to the patient. Pharmacotherapeutic management is directed at minimising these symptoms and reducing the causative factors, e.g. acid production, thereby providing the necessary relief. Currently available agents include simple antacids and acid suppression therapy, including histamine-2 receptor antagonists, proton-pump inhibitors, mucosal or cytoprotective agents and pro-motility agents. Deciding on appropriate therapy will be dependent upon the diagnosis, side-effects and cost-effectiveness of the treatment.