A review of insulin and insulin regimens in type 2 diabetes

  • P Joshi Diabetes Care Centre, Louis Pasteur Medical Centre
  • S Joshi Diabetes Care Centre, Louis Pasteur Medical Centre
Keywords: Insulin, diabetes

Abstract

We have reviewed the various insulins available in the South African market, together with the modes of action of each of the formulations. The insulin groups discussed include the Basal insulins, the bolus or prandial insulins, and the premixed insulins. Furthermore, an approach to the designing of an insulin regimen is discussed, and comments made on how to further intensify therapy depending on the response experienced. Oral hypoglycaemic agent failure is defined by an HbA1C measurement that exceeds 7%, which is a definitive call for further therapy with insulin in type 2 diabetes.

Author Biographies

P Joshi, Diabetes Care Centre, Louis Pasteur Medical Centre
PhD, FRCP ,FRS Med, FICA Emeritus ad hominem Professor, Medical University of Southern Africa Diabetes Care Centre, Louis Pasteur Medical Centre
S Joshi, Diabetes Care Centre, Louis Pasteur Medical Centre
MBChB, MSc(Pharm) Med(UL)
Published
2008-12-11
Section
Clinical